5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione(CAS: 764667-64-3)

5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is a white crystalline solid with a molecular weight of 368.02 g/mol. It is sparingly soluble in water and more soluble in organic solvents. This compound is known for its reactivity in organic synthesis, particularly in condensation reactions.

5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is synthesized via a condensation reaction between a 2,4,5-trifluorophenyl acetaldehyde and 1,3-dioxane-4,6-dione. Commonly, this reaction is catalyzed by acid or base, with a yield of around 70-80%.

5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is used in the pharmaceutical industry for the synthesis of various drugs. It is also applied in the polymer industry for modifying polymer properties and in the semiconductor industry as a dopant.

When handling 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione, wear appropriate personal protective equipment (PPE) including gloves, goggles, and laboratory coat. Work in a well-ventilated area or fume hood. Proper storage and disposal should follow safety data sheet (SDS) guidelines to prevent environmental contamination and ensure safe laboratory conditions.