2,4-Dichloro-6-methylpyrimidine(CAS: 5424-21-5)

2,4-Dichloro-6-methylpyrimidine (CAS: 5424-21-5) is a white crystalline solid with a molecular weight of approximately 214.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and ethanol. The compound exhibits moderate reactivity, particularly towards nucleophiles and reducing agents. It is stable under normal storage conditions but should be kept away from strong oxidizers and reductants.

2,4-Dichloro-6-methylpyrimidine (CAS: 5424-21-5) can be synthesized through the reaction of 6-methylpyrimidine with chlorine gas in the presence of a suitable catalyst such as iron chloride. The synthesis yields a mixture that can be purified by recrystallization or distillation. The process is selective and produces a high yield of the desired product.

2,4-Dichloro-6-methylpyrimidine (CAS: 5424-21-5) is primarily used in the pharmaceutical industry for the synthesis of certain drugs, particularly those requiring pyrimidine derivatives. It is also used in the polymer industry for the development of advanced materials and in semiconductor manufacturing for specific applications.

When handling 2,4-Dichloro-6-methylpyrimidine (CAS: 5424-21-5), ensure proper personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Follow standard laboratory safety guidelines for working with potentially reactive compounds. In case of spills, clean up with appropriate absorbent materials and dispose of waste according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.