2-Fluoro-5-methylaniline(CAS: 452-84-6)

CAS Number
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Basic Information
Molecular Formula
C7H8FN
Molecular Weight
125.15 g/mol
Physical Properties
Boiling Point
90°C/17mmHg(lit.)
Chemical Identifiers
SMILES
CC1=CC(=C(C=C1)F)N
InChIKey
QZUXMXZNVAJNSE-UHFFFAOYSA-N
Database References
MDL Number
MFCD00007654
Beilstein Registry Number
2715995
FAQ
2-Fluoro-5-methylaniline (CAS: 452-84-6) is a white crystalline solid with a molecular weight of approximately 142.04 g/mol. It has a low solubility in water (0.35 g/100 mL at 25°C) but is more soluble in organic solvents like ethanol and acetone. This compound exhibits basic properties due to its amine group and reacts with acids.
2-Fluoro-5-methylaniline (CAS: 452-84-6) is commonly synthesized via the reduction of 2-fluoro-5-methylaniloxyl fluoride. The reaction typically involves the use of a reducing agent like sodium borohydride in an aprotic solvent like dimethylformamide (DMF). This method provides good yield and selectivity.
2-Fluoro-5-methylaniline (CAS: 452-84-6) finds applications in various industries. It is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for the production of functionalized polymers, and in the chemical sensing industry for the development of gas sensors. Additionally, it is used in the electronics industry for semiconductor applications.
When handling 2-Fluoro-5-methylaniline (CAS: 452-84-6), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be done in a fume hood to minimize inhalation risk. Spills should be cleaned up with caution using an appropriate solvent and following the Material Safety Data Sheet (MSDS) guidelines. Proper disposal methods should be followed to ensure environmental safety.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
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