Mono-POC Methyl Tenofovir(CAS: 1246812-16-7)

Mono-POC Methyl Tenofovir is a crystalline compound with a molecular weight of approximately 384.2 g/mol. It has a solubility of 27 mg/mL in water and is sparingly soluble in organic solvents. Chemically, it is highly reactive towards nucleophilic substitution reactions, making it suitable for specific pharmaceutical applications.

Mono-POC Methyl Tenofovir is synthesized via a multi-step process involving the reaction of methyl tenofovir with a phosphorous oxychloride (POCl3), followed by methylation. The reaction is catalyzed by a Lewis acid and proceeds with high yield and good selectivity.

Mono-POC Methyl Tenofovir is primarily used in the pharmaceutical industry for the development of antiretroviral drugs. It is also explored for use in polymer synthesis and as a potential sensor material in certain applications.

When handling Mono-POC Methyl Tenofovir, it is important to wear protective gloves, goggles, and a lab coat. Work under a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.