(1R)-1-(4-Methylphenyl)ethanol(CAS: 42070-92-8)

(1R)-1-(4-Methylphenyl)ethanol is a colorless liquid with a molecular weight of approximately 148.21 g/mol. It has a high boiling point of around 134°C and a low melting point of -26°C. The compound is moderately soluble in water but highly soluble in organic solvents. It exhibits moderate reactivity, particularly in acidic or basic conditions, and is prone to oxidation.

(1R)-1-(4-Methylphenyl)ethanol can be synthesized via reduction of 4-methylbenzaldehyde using sodium borohydride as the reducing agent. The reaction is typically conducted in an aqueous solvent like methanol or ethanol. This method provides a yield of around 75-85%, and the product is isolated by filtration and recrystallization.

(1R)-1-(4-Methylphenyl)ethanol is utilized in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It also finds applications in the production of fragrances and flavorings due to its characteristic aroma. Additionally, it is used in the synthesis of some organic pigments and in the development of certain polymer materials.

When handling (1R)-1-(4-Methylphenyl)ethanol, appropriate personal protective equipment (PPE) such as gloves, safety goggles, and laboratory coat should be worn. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, the area should be ventilated and the spill cleaned up using appropriate absorbents. Emergency showers and eyewash stations should be readily available. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.