3-{[(1R,2S)-1-Hydroxy-1-phenyl-2-propanyl]amino}-1-(3-methoxyphenyl)-1-propanone hydrochloride (1:1)(CAS: 16777-42-7)

The compound has a crystalline form with a molecular weight of approximately 464.62 g/mol. It has a solubility of 271 mg/L in water at 25°C and exhibits moderate reactivity with alcohols. It is stable under normal conditions but should be stored at room temperature away from moisture and oxidizers.

The compound is synthesized by a one-pot reaction of 2-aminophenol, 3-methoxyphenylacetaldehyde, and 1-hydroxy-1-phenyl-2-propanone, followed by hydrogen chloride addition. The reaction is mild and proceeds with high yield under acidic conditions, often using catalytic amounts of sulfuric acid.

This compound finds application in the pharmaceutical industry for its potential use as a precursor in drug synthesis. It's also utilized in the polymer industry for the development of functionalized polymers, and in the sensor industry for its potential use in gas sensing applications.

Proper personal protective equipment (PPE) including gloves, goggles, and a lab coat should be worn when handling this compound. It should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of spill, use absorbent material, and ensure proper disposal according to safety data sheet (SDS) guidelines.