1,3,4-oxadiazole-2-carbaldehyde(CAS: 885270-60-0)

1,3,4-Oxadiazole-2-carbaldehyde (CAS: 885270-60-0) is a crystalline solid with a molecular weight of approximately 136.12 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. The compound is known for its reactive nature, particularly towards nucleophiles, making it suitable for various synthetic transformations.

1,3,4-Oxadiazole-2-carbaldehyde (CAS: 885270-60-0) can be synthesized through the condensation of isoxazole-3-carbaldehyde with hydroxylamine. The process involves the use of anhydrous solvents and typically requires a heating step to drive the reaction to completion. Catalysts such as concentrated sulfuric acid can facilitate the synthesis, leading to good yields and selectivity.

1,3,4-Oxadiazole-2-carbaldehyde (CAS: 885270-60-0) is primarily used in the pharmaceutical industry for the synthesis of complex organic molecules and in the development of new drug candidates. It also finds applications in the polymer industry as a monomer for the production of advanced materials, and in the semiconductor industry as a precursor for electronic materials.

When handling 1,3,4-oxadiazole-2-carbaldehyde (CAS: 885270-60-0), it is crucial to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a fume hood and away from moisture to prevent hydrolysis. In case of a spill, the area should be immediately cleaned up with appropriate absorbent material, and the area should be ventilated. Emergency response procedures and a Safety Data Sheet (SDS) should always be readily available.