Enhancing the conductivity of plasma polymer functionalized electrodes using gold nanoparticles

Literature Information

Publication Date 2023-11-20
DOI 10.1039/D3MA00641G
Impact Factor 0
Authors

Alex Gheorghiu, Daisy Yang, Tiexin Li, Essam M. Dief, Nadim Darwish, Melanie MacGregor


View Original

Abstract

Plasma deposited polyoxazoline thin films (POx) are a promising solution for the rapid, scalable, and substrate-independent immuno-functionalization of electrochemical biosensors. However, a major challenge in using POx thin films in electrochemical sensing is their inherently insulating nature. This work reports the incorporation of gold nanoparticles (AuNPs) between two layers of POx which enhances the conductivity of the films. The size of the AuNPs, their binding density on the POx underlayer, and the POx films’ intrinsic electrical resistance were all factors in improving the overall electrochemical response of the layered construction. Surface bound electrochemical measurements and conductive atomic force microscopy were conducted to uncover a possible mechanism for the observed nanoparticle-mediated electron transport through the insulating matrix. The primary contributor to increasing conductivity in layered constructions is maximising the surface coverage of AuNPs on the surface to provide pathways for current to flow through the insulating matrix. As a proof of concept, POx layered constructions were then used to detect the binding of exosomes to the surface, indicating that these electrodes promise to provide low limits of detection when functionalised with a suitable recognition element.

Related Literature

Enzymatically degradable nanogels by inverse miniemulsion copolymerization of acrylamide with dextran methacrylates as crosslinkers

Daniel Klinger, Eugen M. Aschenbrenner, Clemens K. Weiss, Katharina Landfester

2011-11-18 Paper

DOI: 10.1039/C1PY00415H

Back cover

Cover

DOI: 10.1039/C2PY90021A

Synthesis of poly(p-phenylene vinylene) materials via the precursor routes

Tanja Junkers, Joke Vandenbergh, Peter Adriaensens, Laurence Lutsen

2011-09-23 Review Article

DOI: 10.1039/C1PY00345C

Front cover

Cover

DOI: 10.1039/C2PY90014A

Investigations on the spermine provoked liquid crystalline phase behavior of high molecular weight DNA in the presence of alkali and alkaline earth metal ions

Neethu Sundaresan, Thresia Thomas, T. J. Thomas, C. K. S. Pillai

2011-10-05 Paper

DOI: 10.1039/C1PY00302J

A biocompatible, metal-free catalyst and its application in microwave-assisted synthesis of functional polyesters

Zhengwei You, Eric M. Jeffries, Yadong Wang

2011-11-29 Paper

DOI: 10.1039/C1PY00400J

Upgrading of bio-oil and subsequent co-processing under FCC conditions for fuel production

Udo Armbruster, Hanan Atia, Ursula Bentrup, Binh Minh Quoc Phan, Reinhard Eckelt, Luong Huu Nguyen, Duc Anh Nguyen, Andreas Martin

2015-12-14 Paper

DOI: 10.1039/C5RE00068H

Self-assembled amino acids and dipeptides as noncovalent hydrogels for tissue engineering

Derek M. Ryan, Bradley L. Nilsson

2011-10-07 Review Article

DOI: 10.1039/C1PY00335F

Facile glycosylation of dendrimers for eliciting specific cell–material interactions

Xiaopeng Liu, Jie Liu, Ying Luo

2011-11-29 Communication

DOI: 10.1039/C1PY00404B

You might also like

Compound Q&A

What industries use 4-(4-tert-Butylphenyl)-1H-pyrazol-3-amine (CAS: 1015845-73-4)?

4-(4-tert-Butylphenyl)-1H-pyrazol-3-amine finds applications in various industri...

1015845-73-44-(4-tert-Butylpheny...
Compound Q&A

What industries use H3TATAB (CAS: 63557-10-8)?

H3TATAB is used in the pharmaceutical industry for the synthesis of certain orga...

63557-10-8H3TATAB
Compound Q&A

What are the main uses of 1-Ethyl-3-fluorobenzene (CAS: 696-39-9)?

1-Ethyl-3-fluorobenzene (CAS: 696-39-9) is primarily used as a precursor in the ...

696-39-91-Ethyl-3-fluorobenz...
Compound Q&A

What are the main uses of 1-(tert-Butoxycarbonyl)-4-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid (CAS: 851484-94-1)?

1-(tert-Butoxycarbonyl)-4-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid is prim...

851484-94-11-(tert-Butoxycarbon...
Compound Q&A

What are the physical and chemical properties of 1-Cyclobutyl-4-piperidinone (CAS: 359880-05-0)?

1-Cyclobutyl-4-piperidinone (CAS: 359880-05-0) is a colorless or white crystalli...

359880-05-01-Cyclobutyl-4-piper...
Compound Q&A

What is Pyridine-2,6-dicarboxylic acid mono-tert-butyl ester (CAS: 575433-76-0)?

Pyridine-2,6-dicarboxylic acid mono-tert-butyl ester (CAS: 575433-76-0) is a che...

575433-76-0Pyridine-2,6-dicarbo...
Compound Q&A

What is the market or research trend for 2,3-Difluorophenylalanine (CAS: 236754-62-4)?

The market for 2,3-Difluorophenylalanine (CAS: 236754-62-4) is growing with incr...

236754-62-42,3-Difluorophenylal...
Compound Q&A

How is (2-Hydroxy-1-naphthyl)boronic acid (CAS: 898257-48-2) typically synthesized?

(2-Hydroxy-1-naphthyl)boronic acid can be synthesized through the reduction of 2...

898257-48-2(2-Hydroxy-1-naphthy...
1315351-28-0tert-Butyl (5-bromo-...
Compound Q&A

Are there alternatives to 5,7-Dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)-4H-chromen-3-yl beta-D-glucopyranoside (CAS: 19833-12-6) in synthesis?

While 5,7-Dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)-4H-chromen-3-yl beta-D-gluc...

19833-12-65,7-Dihydroxy-4-oxo-...
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.