Asymmetric synthesis of the two enantiomers of β-phosphorus-containing α-amino acids via hydrophosphinylation and hydrophosphonylation of chiral Ni(ii)-complexes
Literature Information
Yoshinori Tokairin, Hiroyuki Konno, Angéline Noireau, Caroline West, Hiroki Moriwaki, Cyril Nicolas, Isabelle Gillaizeau
A new approach for the asymmetric synthesis of the two enantiomers of β-phosphorus-containing α-amino acids was developed via Michael addition of secondary phosphine oxides and dialkyl phosphites to chiral Ni(II)-complexes of a dehydroalanine-Schiff base.
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