Copper-catalyzed three-component oxycyanation of alkenes
Literature Information
Publication Date
2020-12-25
DOI
10.1039/D0QO01437K
Impact Factor
5.281
Authors
Yuehua Zeng, Yajun Li, Daqi Lv
View Original
Abstract
A copper-catalyzed, three-component reaction for the direct oxycyanation of various alkenes with aryl diacyl peroxides and trimethylsilyl cyanide has been developed. Both unactivated alkenes and styrenes are reliable substrates and produce β-cyanohydrin derivatives. An asymmetric version of this reaction has been conducted and proceeds well.
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