A novel colorimetric and ratiometric fluorescent probe for targeted detection of hypochlorous acid based on HClO-mediated anthracene-hydrazone to anthracene-triazole transformation

Literature Information

Publication Date 2019-07-30
DOI 10.1039/C9AY01234F
Impact Factor 2.896
Authors

Chen Jiang, Yuewei Yao, Chuilian Kong, Jiaqi Du, Jingjing Meng, Cheng Yao


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Abstract

A novel naked-eye colorimetric and ratiometric fluorescent probe (B-ClO) was transformed from anthracene-hydrazone to anthracene-triazole based on a HClO-mediated cyclization reaction with an F434 nm/F570 nm ratio in quantitative response to HClO. The B-ClO probe exhibited high sensitivity (limit of detection of 14 nM) and a fast response time to ClO− over other competing species as well as across a wide pH range. Study of the sensing mechanism supported a HClO-mediated cyclization reaction in which 1,2,4-triazole forms via HClO and a hydrazone derivative, with excellent photophysical properties. Such a probe was used as B-ClO test strips and B-ClO silica materials to monitor HClO in the environment, exhibiting excellent solid properties.

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Analytical Methods

Analytical Methods
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Analytical Methods welcomes early applications of new analytical and bioanalytical methods and technology demonstrating the potential for societal impact. We require that methods and technology reported in the journal are sufficiently innovative, robust, accurate, and compared to other available methods for the intended application. Developments with interdisciplinary approaches are particularly welcome. Systems should be proven with suitably complex and analytically challenging samples. We encourage developments within, but not limited to, the following technologies and applications: global health, point-of-care and molecular diagnostics biosensors and bioengineering drug development and pharmaceutical analysis applied microfluidics and nanotechnology omics studies, such as proteomics, metabolomics or glycomics environmental, agricultural and food science neuroscience biochemical and clinical analysis forensic analysis industrial process and method development

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