Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

Literature Information

Publication Date 2019-10-02
DOI 10.1039/C9AN01312A
Impact Factor 4.616
Authors

Elena Tsolaki, Louis Didierlaurent, Samuel Staubli, Robert Zboray, Antonia Neels, Dörthe Dietrich, Pius Manser, Lotus May Desbiolles, Sebastian Leschka, Simon Wildermuth, Sandro Lehner, Pascale Chavatte-Palmer, Wolfram Jochum, Peter Wick, Tina Bürki-Turnherr, Tina Fischer, René Hornung, Sergio Bertazzo


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Abstract

Despite its crucial role, the placenta is the least understood human organ. Recent clinical studies indicate a direct association between placental calcification and maternal and offspring health. This study reveals distinct characteristics of minerals formed during gestational ageing using cutting-edge nano-analytical characterization and paves the way for investigations focused on the identification of potential markers for disease risks in a clinical setting based on atypical placental mineral fingerprints.

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