Stereocontrolled glycoside synthesis by activation of glycosyl sulfone donors with scandium(iii) triflate

Literature Information

Publication Date 2017-12-12
DOI 10.1039/C7OB02792C
Impact Factor 3.876
Authors

Amandine Xolin, Romain Losa, Aicha Kaid, Cédric Tresse, Stéphanie Norsikian


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Abstract

The activation of aryl glycosyl sulfone donors has been achieved using scandium(III) triflate and has led to the selective preparation of α-mannosides resulting from a post-glycosylation anomerization.

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Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry
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Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

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