Lanthanide coordination polymer nanoparticles as a turn-on fluorescence sensing platform for simultaneous detection of histidine and cysteine
Literature Information
Zhenzhen Zhang, Gaiping Li, Baoxian Ye
In this work, we propose a strategy for the fluorescence assay of histidine (His) and cysteine (Cys) by using lanthanide coordination polymer nanoparticles (Ln-CPN) as a fluorescent probe. The Ln-CPN were prepared by self-assembly of adenosine monophosphate (AMP) with Tb3+, i.e. AMP-Tb. The nonluminescent AMP-Tb could be efficiently sensitized by 5-sulfosalicylic acid (SSA). The fluorescence of AMP-Tb-SSA can be remarkably quenched by Cu2+, and that of the resulting Cu/SSA/AMP-Tb can be significantly enhanced by His and Cys. Thus, a specific fluorescence “turn-on” assay for His and Cys was developed by using Cu/SSA/AMP-Tb as a sensing platform. The enhanced fluorescence intensity was proportional to the His and Cys concentration in the range from 0.2 to 150 μM and 0.5 to 200 μM, respectively, with the detection limits of 70 nM and 100 nM. Additionally, taking advantage of a masking agent for His, the differentiation of His from Cys was achieved in our system. Furthermore, the protocol can also work well for analyzing His and Cys in practical plasma samples with recovery in the range of 100.3–104.1%.
Recommended Journals
Related Literature
Principles of detecting vaporous thiols using liquid crystals and metal ion microarrays
Huan Xu, Xinyan Bi, Xuanming Ngo, Kun-Lin Yang
DOI: 10.1039/B810048A
New advances in on-line sample preconcentration by capillary electrophoresis using dynamic pH junction
Adam S. Ptolemy, Philip Britz-McKibbin
DOI: 10.1039/B808236G
Improving the activity of horseradish peroxidase in betaine-based natural deep eutectic systems
Liane Meneses, Nicolás F. Gajardo-Parra, Esteban Cea-Klapp, José Matías Garrido, Christoph Held, Ana Rita Duarte, Alexandre Paiva
DOI: 10.1039/D2SU00127F
Synthesis of platinum group metal nanoparticles assisted by CO2 reduction and H2 cogeneration at gas-diffusion electrodes
Guillermo Pozo, Luis Fernando Leon-Fernandez, Jan Fransaer, Xochitl Dominguez-Benetton
DOI: 10.1039/D3SU00046J
A microfluidic technique for monitoring bloodstream analytes indicative of C-peptide resistance in type 2 diabetes
Teresa D'Amico Oblak, Jennifer A. Meyer, Dana M. Spence
DOI: 10.1039/B816740K
Facile synthesis of functionalized porous carbon from bitumite mixed with waste powder char for excellent wastewater purification
Yufeng Yin, Yiting Zhao, Jing Wang
DOI: 10.1039/D3SU00064H
Comparative study of poly(styrene-sulfonate)/poly(L-lysine) and fibronectin as biofouling-preventing layers in dissolved oxygen electrochemical measurements
Raphaël Trouillon, Christine Cheung, Bhavik Anil Patel, Danny O'Hare
DOI: 10.1039/B811958A
You might also like
How should 2-Methylbenzene-1,4-diamine dihydrochloride (CAS: 615-45-2) be stored?
2-Methylbenzene-1,4-diamine dihydrochloride (CAS: 615-45-2) should be stored in ...
Is (1S,4S)-2,5-Diazabicyclo[2.2.1]heptane dihydrobromide (CAS: 132747-20-7) safe?
(1S,4S)-2,5-Diazabicyclo[2.2.1]heptane dihydrobromide is generally considered sa...
What industries use (6-Chloropyridazin-3-YL)methanamine (CAS: 871826-15-2)?
(6-Chloropyridazin-3-YL)methanamine finds applications in the pharmaceutical ind...
What are the main uses of 2-Fluoro-3-methylphenol (CAS: 77772-72-6)?
2-Fluoro-3-methylphenol is primarily used in the synthesis of pharmaceuticals, p...
What precautions should be taken when handling 3-Methoxy-4-nitrobenzonitrile (CAS: 177476-75-4)?
When handling 3-Methoxy-4-nitrobenzonitrile, it is important to wear appropriate...
What precautions should be taken when handling 1,3-Oxazolo[4,5-b]pyridine-2(3H)-thione (CAS: 211949-57-4)?
When handling 1,3-Oxazolo[4,5-b]pyridine-2(3H)-thione (CAS: 211949-57-4), it is ...
What regulatory guidelines apply to 4-Ethynylbenzamide (CAS: 90347-86-7)?
4-Ethynylbenzamide (CAS: 90347-86-7) falls under various regulatory guidelines i...
What are the main uses of 3-(2-Ethylphenyl)-2-thioxo-4-imidazolidinone (CAS: 186822-57-1)?
3-(2-Ethylphenyl)-2-thioxo-4-imidazolidinone is primarily used as an intermediat...
What is (2-Fluoro-6-methoxyphenyl)acetic acid (CAS: 500912-19-6)?
(2-Fluoro-6-methoxyphenyl)acetic acid, also known as 4-fluoro-3-methoxybenzoic a...
What is the market or research trend for 2-[4-(Hydroxymethyl)phenoxy]ethanol (CAS: 102196-18-9)?
Market trends for 2-[4-(Hydroxymethyl)phenoxy]ethanol (CAS: 102196-18-9) indicat...
Source Journal
Analyst

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.














