A novel spirocyclic triterpenoid and a new taraxerane triterpenoid from Teucrium viscidum
Literature Information
Publication Date
2016-10-10
DOI
10.1039/C6QO00460A
Impact Factor
5.281
Authors
Zheng-Yu Li, Feng-Ming Qi, De-Juan Zhi, Qiao-Ling Hu, Ying-Hong Liu, Zhan-Xin Zhang, Dong-Qing Fei
View Original
Abstract
Two new triterpenoids, teuviscins A (1) and B (2), were isolated from the whole plants of Teucrium viscidum. Compound 1 possessed a rare 7(8→9)abeo-9R-D:C-friedo-B′:A′-neo-gammacerane skeleton, and compound 2 is a taraxerane triterpene acid. Their structures were characterized by extensive spectroscopic methods (HR-ESI-MS, 1D and 2D NMR), and the absolute configurations of 1 and 2 were secured by single-crystal X-ray diffraction analyses using Cu Kα radiation. Compound 2 showed anti-AD bioactivity which delayed animals paralysis of transgenic AD Caenorhabditis elegans.
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Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
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4-Chloro-N-{[4-(dimethylamino)phenyl]carbamoyl}benzenesulfonamide
CAS Number:
5581-42-0
Molecular Formula:
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3-[7-Amino-3-(3-pyridinyl)pyrazolo[1,5-a]pyrimidin-6-yl]phenol
CAS Number:
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Molecular Formula:
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