Iron-catalyzed trifluoromethylation of vinylcyclopropanes: facile synthesis of CF3–containing dihydronaphthalene derivatives

Literature Information

Publication Date 2016-05-23
DOI 10.1039/C6QO00166A
Impact Factor 5.281
Authors

Zong-Rui Li, Xing-Xing Bao, Jian Sun, Jing Shen, Dun-Qi Wu, Yan-Kai Liu, Qing-Hai Deng, Feng Liu


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Abstract

An efficient Fe(II)-catalyzed trifluoromethylation of vinylcyclopropanes was successfully developed. A series of CF3-containing dihydronaphthalene derivatives were prepared in moderate to high yields (up to 96%) under mild reaction conditions using the Togni reagent as the CF3 source.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
CiteScore: 7.8
Self-citation Rate: 8.7%
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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