Palladium-catalyzed phosphonyldifluoromethylation of alkenes with bromodifluoromethylphosphonate
Literature Information
Publication Date
2016-01-29
DOI
10.1039/C6QO00005C
Impact Factor
5.281
Authors
Zhang Feng, Yu-Lan Xiao, Xingang Zhang
View Original
Abstract
An efficient palladium-catalyzed phosphonyldifluoromethylation of alkenes with bromodifluoromethylphosophonate is described. The method provides a facile access to a series of phosphonyldifluoromethylated alkenes that are of interest in medicinal chemistry. Mechanistic studies reveal that a phosphonyl difluouromethyl radical is involved in the reaction.
Related Literature
Reactive macromolecular micelle crosslinked highly elastic hydrogel with water-triggered shape-memory behaviour
Tingting Zhao, Mei Tan, Yulin Cui, Chao Deng, He Huang, Mingyu Guo
2014-05-07
Paper
DOI: 10.1039/C4PY00554F
Studying the polymerization initiation efficiency of acetophenone-type initiators via PLP-ESI-MS and femtosecond spectroscopy
Hanna A. Ernst, Andreas-Neil Unterreiner
2014-04-29
Paper
DOI: 10.1039/C4PY00418C
Cyclodextrin–calixarene co-polymers as a new class of nanosponges
Paolo Lo Meo, Giuseppe Lazzara, Leonarda Liotta, Serena Riela, Renato Noto
2014-04-03
Paper
DOI: 10.1039/C4PY00325J
Macromolecular covalently cross-linked quaternary ammonium poly(ether ether ketone) with polybenzimidazole for anhydrous high temperature proton exchange membranes
Na Zhang, Chengji Zhao, Wenjia Ma, Shuang Wang, Baolong Wang, Gang Zhang, Xuefeng Li, Hui Na
2014-04-14
Paper
DOI: 10.1039/C4PY00234B
From glycidyl carbonate to hydroxyurethane side-groups in alternating fluorinated copolymers
Roukaya Hamiye, Ali Alaaeddine, Mouhamad Awada, Benjamin Campagne, Sylvain Caillol, Sophie M. Guillaume, Bruno Ameduri, Jean-François Carpentier
2014-05-09
Paper
DOI: 10.1039/C4PY00547C
Low band-gap copolymers derived from fluorinated isoindigo and dithienosilole: synthesis, properties and photovoltaic applications
Zhenguo Wang, Ying Li, Qiang Peng
2014-05-02
Paper
DOI: 10.1039/C4PY00273C
Immortal ring-opening polymerization of ε-caprolactone by a neat magnesium catalyst system: an approach to obtain block and amphiphilic star polymers in situ
Bo Liu, Dongtao Liu, Xinli Liu, Dongmei Cui
2014-05-20
Paper
DOI: 10.1039/C4PY00384E
Highly stable hybrid selenophene-3,4-ethylenedioxythiophene as electrically conducting and electrochromic polymers
Shijie Zhen, Shimin Zhang, Guoqun Zhao
2014-05-29
Paper
DOI: 10.1039/C4PY00529E
You might also like
Compound Q&A
What is Ethyl 3-cyclohexylpropanoate (CAS: 10094-36-7)?
Ethyl 3-cyclohexylpropanoate is a clear, colorless to light yellow liquid with a...
10094-36-7Ethyl 3-cyclohexylpr...
Compound Q&A
How should waste containing 2-(Hydroxymethyl)-5-(methoxycarbonyl)-6-methyl-4-(2-nitrophenyl)nicotinic acid (CAS: 34783-31-8) be handled?
Waste containing 2-(Hydroxymethyl)-5-(methoxycarbonyl)-6-methyl-4-(2-nitrophenyl...
34783-31-82-(Hydroxymethyl)-5-...
Compound Q&A
How should waste containing 2,4,6-Tris(pentafluoroethyl)-1,3,5-triazine (CAS: 858-46-8) be handled?
Waste containing 2,4,6-Tris(pentafluoroethyl)-1,3,5-triazine (CAS: 858-46-8) sho...
858-46-82,4,6-Tris(pentafluo...
Compound Q&A
What precautions should be taken when handling Chloroac-nle-oh (CAS: 56787-36-1)?
When handling Chloroac-nle-oh (CAS: 56787-36-1), it is essential to wear appropr...
56787-36-1Chloroac-nle-oh
Compound Q&A
What industries use Ethyl 6-phenylimidazo[2,1-b][1,3]thiazole-3-carboxylate (CAS: 752244-05-6)?
Ethyl 6-phenylimidazo[2,1-b][1,3]thiazole-3-carboxylate is primarily used in the...
752244-05-6Ethyl 6-phenylimidaz...
Compound Q&A
Are there alternatives to alpha-(2-Bromophenyl)benzylamine (CAS: 55095-15-3) in synthesis?
Alternatives to alpha-(2-Bromophenyl)benzylamine (CAS: 55095-15-3) in synthesis ...
55095-15-3alpha-(2-Bromophenyl...
Compound Q&A
How should waste containing 2-Chloro-5-methoxypyridine (CAS: 139585-48-1) be handled?
Waste containing 2-Chloro-5-methoxypyridine (CAS: 139585-48-1) should be managed...
139585-48-12-Chloro-5-methoxypy...
Compound Q&A
What industries use 1-(4-Methoxyphenyl)-2,5-dimethyl-1H-pyrrole (CAS: 5044-27-9)?
1-(4-Methoxyphenyl)-2,5-dimethyl-1H-pyrrole (CAS: 5044-27-9) is used in various ...
5044-27-91-(4-Methoxyphenyl)-...
Compound Q&A
Are there alternatives to 3-Bromo-5-(N-Boc)aminomethylisoxazole (CAS: 903131-45-3) in synthesis?
There are alternative reagents and compounds that can be used in the synthesis o...
903131-45-33-Bromo-5-(N-Boc)ami...
Compound Q&A
What is Tungsten(IV) oxide (CAS: 12036-22-5)?
Tungsten(IV) oxide, also known as tungsten dioxide, is a chemical compound with ...
12036-22-5Tungsten(IV) oxide
Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
![[2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-3-yl]dicyclohexylphosphane structure](https://static.chemtradehub.com/structs/787/787618-22-8-dda2.webp "[2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-3-yl]dicyclohexylphosphane structure")
[2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-3-yl]dicyclohexylphosphane
CAS Number:
787618-22-8
Molecular Formula:
C30H43O2P
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.