(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetaldehyde
CAS Number:
5614-53-9
Molecular Formula:
C9H10N4O3
Fluorescent RAFT polymers bearing a nitrilotriacetic acid (NTA) ligand at the α-chain-end for the site-specific labeling of histidine-tagged proteins
Literature Information
Publication Date
2017-02-03
DOI
10.1039/C6PY02222G
Impact Factor
5.582
Authors
Zofia Haftek-Terreau, Catherine Ladavière
View Original
Abstract
Site-specific labeling of proteins is a valuable tool to study biological processes. We show that it can be achieved using fluorescent polymer probes synthesized by RAFT polymerization. Thanks to an original control agent functionalized with a nitrilotriacetic acid (NTA) ligand, an α-NTA polymer probe was prepared to selectively label histidine-tagged recombinant proteins.
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Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
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