![4-Fluoro-2-(4-{[(3S,4R)-4-(2-hydroxy-2-propanyl)-3-pyrrolidinyl]amino}-6,7-dimethoxy-2-quinazolinyl)phenol hydrochloride (1:1) structure](https://static.chemtradehub.com/structs/143/1431697-96-9-619c.webp "4-Fluoro-2-(4-{[(3S,4R)-4-(2-hydroxy-2-propanyl)-3-pyrrolidinyl]amino}-6,7-dimethoxy-2-quinazolinyl)phenol hydrochloride (1:1) structure")
4-Fluoro-2-(4-{[(3S,4R)-4-(2-hydroxy-2-propanyl)-3-pyrrolidinyl]amino}-6,7-dimethoxy-2-quinazolinyl)phenol hydrochloride (1:1)
CAS Number:
1431697-96-9
Molecular Formula:
C23H28ClFN4O4
Self-assembled fluorodendrimers in the co-delivery of fluorinated drugs and therapeutic genes
Literature Information
Publication Date
2016-02-25
DOI
10.1039/C6PY00153J
Impact Factor
5.582
Authors
Jingjing Hu, Xiaopan Cai, Jianru Xiao, Yiyun Cheng
View Original
Abstract
Fluorinated drugs now make up about 25% of all pharmaceuticals. However, versatile carriers are currently lacking for the delivery of fluorinated drugs. Here, we developed a fluorodendrimer as a versatile and multifunctional carrier for fluorinated drugs. The fluorodendrimer enables the co-delivery of fluorinated anticancer drugs and therapeutic genes for synergistic cancer therapy.
Related Literature
Red fluorescent cross-linked glycopolymer nanoparticles based on aggregation induced emission dyes for cell imaging
Ke Wang, Xiqi Zhang, Bin Yang, Zhen Li, Qingsong Zhang, Zengfang Huang, Yen Wei
2014-11-27
Paper
DOI: 10.1039/C4PY01452A
Synthesis, kinetics, and characterization of bio-based thermosets obtained through polymerization of a 2,5-furandicarboxylic acid-based bis(2-oxazoline) with sebacic acid
Nino J. M. Wullems, Erik Gubbels, Yefen Yao, Bart A. J. Noordover
2015-02-13
Paper
DOI: 10.1039/C4PY01609B
Synthesis of well-defined α,ω-telechelic multiblock copolymers in aqueous medium: in situ generation of α,ω-diols
Alexandre Simula, Vasiliki Nikolaou, Athina Anastasaki, Fehaid Alsubaie, Gabit Nurumbetov
2015-01-16
Paper
DOI: 10.1039/C4PY01802H
A low band-gap copolymer composed of thienyl substituted anthracene and diketopyrrolopyrrole compatible with multiple electron acceptors for high efficiency polymer solar cells
Jae Woong Jung, Won Ho Jo
2015-04-20
Paper
DOI: 10.1039/C5PY00358J
Amphiphilic and double hydrophilic block copolymers containing a polydehydroalanine block
Peter Bellstedt
2016-12-22
Paper
DOI: 10.1039/C6PY02076C
NIR-responsive polypeptide copolymer upconversion composite nanoparticles for triggered drug release and enhanced cytotoxicity
Gang Liu, Na Liu, Linzhu Zhou, Yue Su, Chang-Ming Dong
2015-04-21
Paper
DOI: 10.1039/C5PY00479A
Facile synthesis of well-defined redox responsive diselenide-labeled polymers via organoselenium-mediated CRP and aminolysis
Feng Gao, Xiangqiang Pan, Jian Zhu, Zhengbiao Zhang, Wei Zhang, Xiulin Zhu
2014-11-19
Paper
DOI: 10.1039/C4PY01481B
Unraveling the forming mechanism of hierarchical helices via self-assembly of an achiral supramolecular polymer brush
Shanshan Liu, Qibin Chen, Yujie Sheng, Jincheng Shen, Changjun Peng, Honglai Liu
2015-03-23
Paper
DOI: 10.1039/C5PY00163C
Hypersulfonated polyelectrolytes: preparation, stability and conductivity
Andreas Wohlfarth, Angelika Manhart, Petra Räder, Patric Jannasch
2014-11-18
Paper
DOI: 10.1039/C4PY01177E
You might also like
Compound Q&A
What are the main uses of (5-Sulfamoyl-3-pyridinyl)boronic acid (CAS: 951233-61-7)?
(5-Sulfamoyl-3-pyridinyl)boronic acid is primarily used in chemical synthesis, p...
951233-61-7(5-Sulfamoyl-3-pyrid...
Compound Q&A
How is Benzyl 2-methyl-2-(methylsulfonyl)-4-pentenoate (CAS: 1942858-50-5) typically synthesized?
Benzyl 2-methyl-2-(methylsulfonyl)-4-pentenoate is typically synthesized via est...
1942858-50-5Benzyl 2-methyl-2-(m...
Compound Q&A
What precautions should be taken when handling 8-Fluoroquinolin-6-ol (CAS: 209353-22-0)?
When handling 8-Fluoroquinolin-6-ol (CAS: 209353-22-0), it is important to use p...
209353-22-08-Fluoroquinolin-6-o...
Compound Q&A
What are the physical and chemical properties of 1,3-Dibromo-5-(2-methyl-2-propanyl)benzene (CAS: 129316-09-2)?
1,3-Dibromo-5-(2-methyl-2-propanyl)benzene (CAS: 129316-09-2) is a crystalline c...
129316-09-21,3-Dibromo-5-(2-met...
Compound Q&A
What industries use Ethyl 7-chloro-4-oxo-1-(1,3-thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylate (CAS: 174726-87-5)?
Ethyl 7-chloro-4-oxo-1-(1,3-thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine-3-carbox...
174726-87-5Ethyl 7-chloro-4-oxo...
Compound Q&A
What precautions should be taken when handling Delta-7-Avenasterol (CAS: 23290-26-8)?
When handling Delta-7-Avenasterol (CAS: 23290-26-8), it is important to wear app...
23290-26-8Delta-7-Avenasterol
Compound Q&A
What precautions should be taken when handling N-({(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide (CAS: 872992-20-6)?
Proper handling involves the use of personal protective equipment such as gloves...
872992-20-6N-({(5R)-3-[3-Fluoro...
Compound Q&A
What precautions should be taken when handling 2-Methyl-2-proanyl 4-[(2-aminophenyl)amino]-1-piperidinecarboxylate (CAS: 79099-00-6)?
When handling 2-Methyl-2-proanyl 4-[(2-aminophenyl)amino]-1-piperidinecarboxylat...
79099-00-62-Methyl-2-propanyl ...
Compound Q&A
What is N-Methyl-4-chlorobenzylamine hydrochloride (CAS: 65542-24-7)?
N-Methyl-4-chlorobenzylamine hydrochloride (CAS: 65542-24-7) is a organic compou...
65542-24-7N-Methyl-4-chloroben...
Compound Q&A
Is [2-(Dodecyloxy)ethoxy]acetic acid (CAS: 27306-90-7) safe?
[2-(Dodecyloxy)ethoxy]acetic acid (CAS: 27306-90-7) is generally considered safe...
27306-90-7[2-(Dodecyloxy)ethox...
Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
Recommended Compounds
![2-Methyl-2-propanyl 4-oxo-3,9-diazabicyclo[4.2.1]nonane-9-carboxylate structure](https://static.chemtradehub.com/structs/131/1312456-05-5-9a15.webp "2-Methyl-2-propanyl 4-oxo-3,9-diazabicyclo[4.2.1]nonane-9-carboxylate structure")
2-Methyl-2-propanyl 4-oxo-3,9-diazabicyclo[4.2.1]nonane-9-carboxylate
CAS Number:
1312456-05-5
Molecular Formula:
C12H20N2O3
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.