Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

Literature Information

Publication Date 2016-05-12
DOI 10.1039/C6AN00735J
Impact Factor 4.616
Authors

Zhichao Pei, Björn Ingemarsson, Teodor Aastrup, Olof Ramström


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Abstract

The signal enhancement properties of QCM sensors based on dynamic, biotinylated poly(acrylic acid) brushes has been studied in interaction studies with an anti-biotin Fab fragment. The poly(acrylic acid) sensors showed a dramatic increase in signal response with more than ten times higher signal than the carboxyl-terminated self-assembled monolayer surface.

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