Cu-catalyzed sequential C–N bond formations: expeditious synthesis of tetracyclic indoloindol-3-ones
Literature Information
Publication Date
2015-11-03
DOI
10.1039/C5QO00248F
Impact Factor
5.281
Authors
Anand M. Kulkarni, Kolluru Srinivas, Mukund V. Deshpande, Chepuri V. Ramana
View Original
Abstract
The tetracyclic indoloindol-3-one core has been forged from easily accessible 2,2′-bis-bromochalcones employing a reaction cascade comprising Cu-catalyzed SNAr with azide; nitrene C–H insertion and intramolecular Ullmann reaction with all three C–N bond formations in one-go.
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Organic Chemistry Frontiers
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