Organoselenium-catalyzed synthesis of indoles through intramolecular C–H amination

Literature Information

Publication Date 2015-07-29
DOI 10.1039/C5QO00179J
Impact Factor 5.281
Authors

Xuelin Zhang, Ruizhi Guo, Xiaodan Zhao


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Abstract

A new and efficient route for organoselenium-catalyzed synthesis of indoles via intramolecular C–H amination has been developed. The reaction conditions were mild and the desired products were formed in up to 99% yield. When the method was applied in the reaction of a trisubstituted alkene, the corresponding indole was obtained in 99% yield via 1,2-phenyl migration.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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