DNA molecular recognition of intercalators affects aggregation of a thermoresponsive polymer

Literature Information

Publication Date 2014-05-07
DOI 10.1039/C4PY00600C
Impact Factor 5.582
Authors

Yuuki Sugawara, Takanori Tamaki, Takeo Yamaguchi


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Abstract

Binding of intercalators to dsDNA switches the aggregation phenomena of DNA–PNIPAM because the binding decreases the dsDNA conformational entropy and/or the shielding of dsDNA charges. Thus, dsDNA–PNIPAM was dramatically aggregated in response to molecular recognition of the DNA–intercalator.

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Polymer Chemistry

Polymer Chemistry
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