Self-assembly of plasma protein through disulfide bond breaking and its use as a nanocarrier for lipophilic drugs
Literature Information
Publication Date
2014-05-16
DOI
10.1039/C4PY00212A
Impact Factor
5.582
Authors
Shudong Wang, Guangming Gong, Hua Su, Wenya Liu, Zhen Wang, Li Li
View Original
Abstract
A disulfide bond breaking strategy used to fabricate HSA nanoparticles with dithiothreitol as the reducing agent is presented. The hydrophobic interaction is a dominating factor in the assembly process. These nanoparticles are suitable lipophilic drug delivery systems, which have significant tumor-targeting capabilities.
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Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
Recommended Compounds
![[2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-3-yl]dicyclohexylphosphane structure](https://static.chemtradehub.com/structs/787/787618-22-8-dda2.webp "[2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-3-yl]dicyclohexylphosphane structure")
[2',6'-bis(propan-2-yloxy)-[1,1'-biphenyl]-3-yl]dicyclohexylphosphane
CAS Number:
787618-22-8
Molecular Formula:
C30H43O2P
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