Structural–functional evaluation of ionic liquid libraries for the design of co-solvents in lipase-catalysed reactions
Literature Information
João V. Rodrigues, Diana Ruivo, Ana Rodríguez, Francisco J. Deive, José M. S. S. Esperança, Isabel M. Marrucho, Cláudio M. Gomes, Luís Paulo N. Rebelo
Using ionic liquids as co-solvents may improve reaction media in enzyme-based biotechnological processes. To establish new conditions, large libraries need to be screened for bio-compatibility and protein stabilisation. Using a lipase model, we herein describe a combination of methods leading to an expedited evaluation of 61 different solvent compositions.
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