A highly sensitive and reductant-resistant fluorescent probe for nitroxyl in aqueous solution and serum

Literature Information

Publication Date 2014-04-01
DOI 10.1039/C4CC01440E
Impact Factor 6.222
Authors

Guo-Jiang Mao, Xiao-Bing Zhang, Xue-Lin Shi, Hong-Wen Liu, Yong-Xiang Wu, Li-Yi Zhou, Weihong Tan, Ru-Qin Yu


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Abstract

A novel coumarin-based fluorescent probe, P-CM, for quantitative detection of nitroxyl (HNO) was developed. P-CM exhibits a selective response to HNO over other biological reductants and was also applied for quantitative detection of HNO in bovine serum with satisfactory results.

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Chemical Communications

Chemical Communications
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ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

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