High resolution Raman spectroscopy mapping of stem cell micropatterns

Literature Information

Publication Date 2015-02-11
DOI 10.1039/C4AN02346C
Impact Factor 4.616
Authors

Thomas C. von Erlach, Molly M. Stevens


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Abstract

We report on the use of high resolution Raman spectroscopy mapping combined with a micro-engineered stem cell platform. This technique obtains quantitative information about the concentration of individual intracellular molecules such as proteins, lipids, and other metabolites, while tightly controlling cell shape and adhesion. This new quantitative analysis will prove highly relevant for in vitro drug screening applications and regenerative medicine.

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