Single-chain polymernanoparticlesvia reversible disulfide bridges
Literature Information
Bryan T. Tuten, Christopher K. Lyon
We report the fabrication of single-chain polymer nanoparticles (SCNP) that can reversibly undergo a coil to particle transition via formation and cleavage of intramolecular disulfide cross-links. Characterization of this behaviour via shifts in SEC retention time confirm the changes in solution conformation in response to oxidative or reductive stimuli.
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