Silver triflate and N-heterocyclic carbene co-catalyzed reaction of N′-(2-alkynylbenzylidene)hydrazide, methanol with α,β-unsaturated aldehyde
Literature Information
Zhiyuan Chen, Xingxin Yu
A highly efficient silver triflate and N-heterocyclic carbene co-catalyzed three-component reaction of N′-(2-alkynylbenzylidene)hydrazide, methanol with α,β-unsaturated aldehyde is described, which gives rise to the 2-amino-1,2-dihydroisoquinolines in good yield.
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![5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(S-methylsulfonimidoyl)methyl]-2-pyridinyl}-2-pyridinamine structure 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(S-methylsulfonimidoyl)methyl]-2-pyridinyl}-2-pyridinamine structure](https://static.chemtradehub.com/structs/161/1610358-53-6-afd1.webp)

