Recent extensions of the Morita–Baylis–Hillman reaction

Literature Information

Publication Date 2009-08-13
DOI 10.1039/B909405A
Impact Factor 6.222
Authors

Guang-Ning Ma, Jia-Jun Jiang, Yin Wei


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Abstract

Significant progress in the development of the Morita–Baylis–Hillman (MBH) reaction has been made in the past decade. Many new variations of the MBH reaction have been well exploited, affording unexpected products and novel cyclized adducts in some cases, known as “abnormal MBH reactions”. The formation of abnormal MBHadducts depends on the nature of the substrates and the employed catalytic system. This article will summarize recent advances in and mechanistic insights into such “abnormal” MBH reactions, including double-MBH reactions, sila-MBH reactions, abnormal aza-MBH reactions and tandem MBH pathways.

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