Dynamic kinetic resolution of β-keto sulfonesvia asymmetric transfer hydrogenation
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Zhenhua Ding, Jin Yang, Ting Wang, Zongxuan Shen, Yawen Zhang
The dynamic kinetic resolution of β-keto sulfones was achieved via asymmetric transfer hydrogenation using (S,S)-RuCl[N-(tosyl)-1,2-diphenylethylenediamine](p-cymene) in the presence of formic acid and triethylamine afforded the desired products in good yield with up to >99 : 1 dr and high ee up to >99%.
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