Ruthenium polypyridyl peptide conjugates: membrane permeable probes for cellular imaging
Literature Information
Ute Neugebauer, Yann Pellegrin, Marc Devocelle, William Signac, Niamh Moran
Two novel polyarginine labelled ruthenium polypyridyl dyes are reported, one conjugated to five, (Ru–Ahx–R5), and one to eight arginine residues, (Ru–Ahx–R8); both complexes exhibit long-lived, intense, and oxygen-sensitive luminescence; (Ru–R8) is passively, efficiently and very rapidly transported across the cell membrane into the cytoplasm without requirement for its permeablisation.
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![Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, compd. with 1-pyrrolidineethanol (1:1) structure Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, compd. with 1-pyrrolidineethanol (1:1) structure](https://static.chemtradehub.com/structs/119/119623-66-4-5301.webp)

