Selective synthesis of double temperature-sensitive polymer–peptide conjugates

Literature Information

Publication Date 2008-07-16
DOI 10.1039/B806782A
Impact Factor 6.222
Authors

Florentina Stoica, Cameron Alexander, Nicola Tirelli, Aline F. Miller, Alberto Saiani


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Abstract

A novel synthetic route has been developed to couple selectively a modified octa-peptide, that is able to gel at low temperature, to the prototypical thermoresponsive polymer poly(N-isopropylacrylamide) to give a bioconjugate that exhibits double thermoresponsiveness.

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