In tube determination of the absolute configuration of α- and β-hydroxy acids by NMR via chiral BINOL borates
Literature Information
Félix Freire, Emilio Quiñoá, Ricardo Riguera
A simple NMR methodology, through the formation of chiral BINOL borates in the NMR tube, and that reunites the advantages of chiral derivatizing (CDAs) and chiral solvating agents (CSAs), is presented for the assignment of the absolute configuration of α- and β-hydroxy acids.
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