Anti-Markovnikov hydroarylation of styrenes catalyzed by an in situ generated ruthenium complex

Literature Information

Publication Date 2008-06-24
DOI 10.1039/B806121A
Impact Factor 6.222
Authors

Rémi Martinez, Jean-Pierre Genet, Sylvain Darses


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Abstract

An efficient and practical catalytic system for the anti-Markovnikov ruthenium-catalyzed hydroarylation of styrenes with acetophenone, allowing a straightforward access to bibenzyl backbones, is described for the first time: this process, involving regioselective C–H bond activation, is complementary to a Friedel–Crafts type reaction giving the branched adduct.

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