Carboranyl thymidine analogues for neutron capture therapy

Literature Information

Publication Date 2007-08-15
DOI 10.1039/B707257K
Impact Factor 6.222
Authors

Rohit Tiwari, Youngjoo Byun, Sureshbabu Narayanasamy


View Original

Abstract

Neutron capture therapy (NCT) is a binary radio-chemotherapeutic modality for the treatment of cancer. A major focus of NCT-related research is the development of novel tumor-selective agents that serve as the chemical component in NCT. Thymidine analogues substituted with a boron-containing carborane cluster at the N3 position, designated 3CTAs (3-carboranyl thymidine analogues), constitute one class of these new improved NCT agents. Their chemical, structural and biological properties are discussed in this Feature Article.

Related Literature

Air-stable and efficient inorganic–organic heterojunction solar cells using PbS colloidal quantum dots co-capped by 1-dodecanethiol and oleic acid

Sang Hyuk Im, Meejae Kang, Jin Hyuck Heo, Sang Il Seok, Sang-Wook Kim, Iván Mora-Seró, Juan Bisquert

2012-09-18 Communication

DOI: 10.1039/C2CP43223D

Connecting the (quantum) dots: towards hybrid photovoltaic devices based on chalcogenide gels

Jilian N. De Freitas, Lasantha Korala, Luke X. Reynolds, Saif A. Haque, Stephanie L. Brock, Ana F. Nogueira

2012-09-12 Paper

DOI: 10.1039/C2CP42998E

Experimental and DFT study of thiol-stabilized Pt/CNTs catalysts‡

L. Li, S. G. Chen, Z. D. Wei, X. Q. Qi, M. R. Xia, Y. Q. Wang

2012-07-17 Paper

DOI: 10.1039/C2CP41346A

Rapid determination of entropy and free energy of mixtures from molecular dynamics simulations with the two-phase thermodynamic model

Pin-Kuang Lai, Chieh-Ming Hsieh, Shiang-Tai Lin

2012-09-17 Paper

DOI: 10.1039/C2CP42011B

First-principles simulation of the absorption bands of fluorenone in zeolite L

Xiuwen Zhou, Tomasz A. Wesolowski, Gloria Tabacchi, Ettore Fois, Gion Calzaferri, André Devaux

2012-10-18 Paper

DOI: 10.1039/C2CP42750H

Theoretical and experimental studies of water interaction in acetate based ionic liquids

Krishnan Damodaran, Hunaid B. Nulwala, David R. Luebke

2012-10-08 Paper

DOI: 10.1039/C2CP42975F

A titanium-based oxysulfide photocatalyst: La5Ti2MS5O7 (M = Ag, Cu) for water reduction and oxidation

Takahiro Suzuki, Takashi Hisatomi, Kentaro Teramura, Yoshiki Shimodaira, Hisayoshi Kobayashi, Kazunari Domen

2012-09-25 Paper

DOI: 10.1039/C2CP43132G

Is C60 buckminsterfullerene aromatic?

Zhongfang Chen, Judy I. Wu, Clémence Corminboeuf, Jonathan Bohmann, Xin Lu, Andreas Hirsch, Paul von Ragué Schleyer

2012-08-13 Paper

DOI: 10.1039/C2CP42146A

Contents list

Front/Back Matter

DOI: 10.1039/C2CP90157A

You might also like

Compound Q&A

What precautions should be taken when handling 4-Methyl-6-(trifluoromethyl)quinoline (CAS: 40716-16-3)?

When handling 4-Methyl-6-(trifluoromethyl)quinoline (CAS: 40716-16-3), safety go...

40716-16-34-Methyl-6-(trifluor...
Compound Q&A

What is 4-(3,5-Difluorophenyl)aniline (CAS: 405058-00-6)?

4-(3,5-Difluorophenyl)aniline is an aromatic organic compound with the CAS numbe...

405058-00-64-(3,5-Difluoropheny...
Compound Q&A

How is 5-{[4-(Trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylic acid (CAS: 338982-07-3) typically synthesized?

5-{[4-(Trifluoromethyl)phenyl]sulfanyl}-1,2,3-thiadiazole-4-carboxylic acid can ...

338982-07-35-{[4-(Trifluorometh...
Compound Q&A

What is the market or research trend for 4-Benzylaniline hydrochloride (CAS: 6317-57-3)?

The market for 4-Benzylaniline hydrochloride (CAS: 6317-57-3) is steadily growin...

6317-57-34-Benzylaniline hydr...
Compound Q&A

Is [3-(Diethylsulfamoyl)phenyl]boronic acid (CAS: 871329-58-7) safe?

[3-(Diethylsulfamoyl)phenyl]boronic acid is generally considered safe when handl...

871329-58-7[3-(Diethylsulfamoyl...
Compound Q&A

What are the main uses of 3-Bromo-2,5-dimethoxyaniline (CAS: 115929-62-9)?

3-Bromo-2,5-dimethoxyaniline is mainly used in the pharmaceutical and chemical i...

115929-62-93-Bromo-2,5-dimethox...
Compound Q&A

What regulatory guidelines apply to N-Methyl-1-(5-methyl-1H-indol-3-yl)methanamine (CAS: 915922-67-7)?

N-Methyl-1-(5-methyl-1H-indol-3-yl)methanamine (CAS: 915922-67-7) is subject to ...

915922-67-7N-Methyl-1-(5-methyl...
Compound Q&A

What industries use Carbamic acid, N-[(5S)-5,6-diamino-6-oxohexyl]-, 1,1-dimethylethyl ester (CAS: 24828-96-4)?

This compound is primarily used in the pharmaceutical industry for the synthesis...

24828-96-4Carbamic acid, N-[(5...
Compound Q&A

How should 2-Methyl-2-propanyl [(1S,3R)-3-aminocyclohexyl]carbamate (CAS: 1298101-47-9) be stored?

2-Methyl-2-propanyl [(1S,3R)-3-aminocyclohexyl]carbamate (CAS: 1298101-47-9) sho...

1298101-47-92-Methyl-2-propanyl ...
Compound Q&A

What industries use Ethyl 2-bromo-4,4,4-trifluorobutanoate (CAS: 367-33-9)?

Ethyl 2-bromo-4,4,4-trifluorobutanoate (CAS: 367-33-9) is utilized in the pharma...

367-33-9Ethyl 2-bromo-4,4,4-...

Source Journal

Chemical Communications

Chemical Communications
CiteScore: 8.6
Self-citation Rate: 4.7%
Articles per Year: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.