Conformational control of HCl co-transporter: imidazole functionalised isophthalamidevs. 2,6-dicarboxamidopyridine
Literature Information
Philip A. Gale, Joachim Garric, Mark E. Light, Beth A. McNally, Bradley D. Smith
Replacement of the central isophthalamide core in a synthetic HCl receptor, with a 2,6-dicarboxamidopyridine, leads to a more preorganised molecular structure that exhibits higher chloride affinity and membrane transport flux.
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