Stereoselective construction of fluorinated indanone derivatives via a triple cascade Lewis acid-catalyzed reaction

Literature Information

Publication Date 2007-04-04
DOI 10.1039/B702114C
Impact Factor 6.222
Authors

Han-Feng Cui, Ke-Yan Dong, Guang-Wu Zhang, Lian Wang


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Abstract

A one-pot three-component cascade reaction proceeds by way of a Lewis acid-catalyzed Knoevenagel condensation/Nazarov cyclization/electrophilic fluorination sequence to afford fluorinated 1-indanone derivatives in moderate to good yields with high diastereoselectivities.

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