Asymmetric total synthesis of martinelline and martinellic acid

Literature Information

Publication Date 2006-11-01
DOI 10.1039/B611121A
Impact Factor 6.222
Authors

Shuhei Ikeda, Masatoshi Shibuya, Yoshiharu Iwabuchi


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Abstract

Herein, we describe the first asymmetric total synthesis of (–)-martinelline ((–)-2) and the second total synthesis of (–)-martinellic acid ((–)-1) by employing a tandem Mukaiyama–Mannich reaction/aminal cyclization as the key step.

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