The direct α-zincation of amides, phosphonates and phosphine oxides by H–Zn exchange
Literature Information
Mark L. Hlavinka, Jeffrey F. Greco, John R. Hagadorn
Stoichiometric or catalytic quantities of simple 2° amines greatly increase the rate of H–Zn exchange between ZnPh2 and a range of relatively non-acidic substrates, allowing for the convenient and direct preparation of α-functionalized organozincs.
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