Biofunctionalization of fluorescent-magnetic-bifunctional nanospheres and their applications

Literature Information

Publication Date 2005-08-08
DOI 10.1039/B508075D
Impact Factor 6.222
Authors

Guo-Ping Wang, Er-Qun Song, Hai-Yan Xie, Zhi-Ling Zhang, Zhi-Quan Tian, Chao Zuo, Dai-Wen Pang, Dao-Cheng Wu, Yun-Bo Shi


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Abstract

Hydrazide-containing bifunctional nanospheres were covalently coupled on the surface with IgG, avidin, and biotin, to generate novel fluorescent-magnetic-biotargeting trifunctional nanospheres, which can be used in a number of biomedical applications, including visual sorting and manipulation of apoptotic cells as demonstrated here.

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