Targeting of mixed sequence double-stranded DNA using pyrene-functionalized 2′-amino-α-l-LNA
Literature Information
Patrick J. Hrdlicka, T. Santhosh Kumar, Jesper Wengel
Incorporation of a single pyrene-functionalized 2′-amino-α-L-LNA monomer X into short DNA strands induces extraordinarily high binding affinity towards complementary DNA (up to 16 °C increase per modification), whereas labile duplexes, suitable as probes for targeting of double stranded DNA, are formed upon positioning of two monomers X in an interstrand +1 zipper motif.
Related Literature
The role of Caenorhabditis elegans in the discovery of natural products for healthy aging
Benjamin Kirchweger, Julia Zwirchmayr, Ulrike Grienke, Judith M. Rollinger
DOI: 10.1039/D3NP00021D
Unraveling ligand exchange reactions in linear neutral Au(i) and Cu(i) N-heterocyclic carbene complexes for biological applications
Gustavo C. Rodrigues, Manoel V. F. Barrionuevo, Miguel A. San-Miguel, Camilla Abbehausen
DOI: 10.1039/D3NJ04945K
Structure influence on high-pressure water intrusion in pure silica zeolites
DOI: 10.1039/D3NJ03991A
A biscationic imidazolium ionic liquid immobilized on graphene oxide as an efficient heterogeneous catalyst for the synthesis of tetraketone derivatives
Padmini Gupta, Bholey Singh, Manjeet Dhama, Balaram Pani, Subho Mozumdar
DOI: 10.1039/D3NJ03812B
Structural insights into the diverse prenylating capabilities of DMATS prenyltransferases
Evan T. Miller, Oleg V. Tsodikov, Sylvie Garneau-Tsodikova
DOI: 10.1039/D3NP00036B
Development of highly sensitive/durable porous carbon nanotube–polydimethylsiloxane sponge electrode for wearable human motion monitoring sensor
Sung-Jun Lee, Yoon-Gyung Sung, Santhia Kesavan, Chang-Lae Kim
DOI: 10.1039/D3NJ04802K
A low cost Zn2+/I− redox active electrolyte for a high energy and long cycle-life zinc hybrid battery–capacitor
Balamurugan Selvaraj, Balaji Sambandam, Sungjin Kim, Vinod Mathew, Sehong Seo, Moonsu Song, Jaekook Kim
DOI: 10.1039/D3TA03912A
Enhancing Li+ transport efficiency in solid-state Li-ion batteries with a ceramic-array-based composite electrolyte
Shu-Ming Yeh, Chia-Chen Li
DOI: 10.1039/D3TA05329F
Design and numerical-phase analysis of an SPR system for direct detection of SARS-CoV-2 virus in pharyngeal swab solution
Yansheng Liu, Xiaobo Jia, Jin Zhou, Hongli Li, Xiaohong Wang, Yating Chen, Zhenle Qin, Zhichen Jin, Guofu Wang
DOI: 10.1039/D3NJ05083A
You might also like
How should waste containing N-Methoxy-N-methyl-1,3-thiazole-5-carboxamide (CAS: 898825-89-3) be handled?
Waste containing N-Methoxy-N-methyl-1,3-thiazole-5-carboxamide (CAS: 898825-89-3...
How should N-(4-Biphenylyl)dibenzo[b,d]furan-4-amine (CAS: 1318338-47-4) be stored?
N-(4-Biphenylyl)dibenzo[b,d]furan-4-amine should be stored in a tightly sealed c...
What is the market or research trend for 3-Acetamido-5-amino-2,4,6-triiodobenzoic acid (CAS: 1713-07-1)?
The market for 3-Acetamido-5-amino-2,4,6-triiodobenzoic acid (CAS: 1713-07-1) is...
How should Benzyl 2-O-acetyl-3,4,6-tri-O-benzyl-beta-D-galactopyranoside (CAS: 61820-03-9) be stored?
Benzyl 2-O-acetyl-3,4,6-tri-O-benzyl-beta-D-galactopyranoside (CAS: 61820-03-9) ...
What regulatory guidelines apply to 2-Ethylpiperazine dihydrochloride (CAS: 438050-52-3)?
2-Ethylpiperazine dihydrochloride (CAS: 438050-52-3) is regulated under the Glob...
What regulatory guidelines apply to 1,1'-[1,3-Phenylenebis(methylene)]bis(3-methyl-1H-pyrrole-2,5-dione) (CAS: 119462-56-5)?
1,1'-[1,3-Phenylenebis(methylene)]bis(3-methyl-1H-pyrrole-2,5-dione) (CAS: 11946...
Are there alternatives to 5-Fluoro-2-(1-pyrrolidinyl)pyridine (CAS: 1287217-79-1) in synthesis?
Several alternatives can be used in the synthesis of 5-Fluoro-2-(1-pyrrolidinyl)...
What precautions should be taken when handling 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (CAS: 153631-19-7)?
Proper personal protective equipment (PPE) must be worn when handling this compo...
What precautions should be taken when handling 6-Bromoimidazo[1,2-a]pyridin-8-amine (CAS: 676371-00-9)?
When handling 6-Bromoimidazo[1,2-a]pyridin-8-amine, it is important to wear appr...
Are there alternatives to (2S,4R)-4-(4-Nitrobenzyl)pyrrolidine-2-carboxylic acid hydrochloride (CAS: 1049740-22-8) in synthesis?
Alternatives to (2S,4R)-4-(4-Nitrobenzyl)pyrrolidine-2-carboxylic acid hydrochlo...
Source Journal
Chemical Communications

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry











![4-Chloro-2-{[(2-chlorophenoxy)acetyl]amino}benzoic acid structure 4-Chloro-2-{[(2-chlorophenoxy)acetyl]amino}benzoic acid structure](https://static.chemtradehub.com/structs/351/351424-20-9-9467.webp)


![4-[(2-{2-[2-(2-Aminoethoxy)ethoxy]ethoxy}ethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione structure 4-[(2-{2-[2-(2-Aminoethoxy)ethoxy]ethoxy}ethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione structure](https://static.chemtradehub.com/structs/209/2093416-31-8-3162.webp)