Fine tuning the structure of the Cu2+ complex with the prion protein chicken repeat by proline isomerization

Literature Information

Publication Date 2005-06-01
DOI 10.1039/B504986E
Impact Factor 6.222
Authors

Paweł Stańczak, Daniela Valensin, Paulina Juszczyk, Zbigniew Grzonka, Gianni Valensin, Francesca Bernardi, Elena Molteni, Elena Gaggelli, Henryk Kozłowski


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Abstract

The interaction between the single hexarepeat unit of chicken prion protein [ChPrP(54–59)] and Cu(II) was investigated by NMR, finding different coordination modes for the trans/trans and cis/trans isomers.

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