Rhodium/diene-catalyzed asymmetric 1,4-addition of arylboronic acids to α,β-unsaturated Weinreb amides

Literature Information

Publication Date 2005-05-18
DOI 10.1039/B502921J
Impact Factor 6.222
Authors

Ryo Shintani, Takahiro Kimura, Tamio Hayashi


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Abstract

Rhodium/chiral diene (S,S)-3b complex has been found to effectively catalyze the 1,4-addition of arylboronic acids to α,β-unsaturated Weinreb amides, furnishing useful β-chiral Weinreb amides in high enantioselectivity.

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