Study of the Michael addition of β-cyclodextrin–thiol complexes to conjugated alkenes in water

Literature Information

Publication Date 2004-12-14
DOI 10.1039/B411736K
Impact Factor 6.222
Authors

N. Srilakshmi Krishnaveni, K. Surendra, K. Rama Rao


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Abstract

An environmentally benign and highly efficient supramolecular Michael addition of thiols from the secondary side of β-cyclodextrin to α,β-unsaturated compounds at the primary side in water is described in quantitative yields; products of undesirable side reactions resulting from polymerization are not observed; the use of cyclodextrin precludes the use of either acid or base and the catalyst can be recovered and reused.

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