Direct intramolecular arylation of unactivated arenes: application to the synthesis of aporphine alkaloids
Literature Information
Marc Lafrance, Nicole Blaquière, Keith Fagnou
The direct intramolecular C–H arylation of unactivated arenes is a viable strategy for the synthesis of aporphine alkaloids. These reactions occur with 3 to 5 mol% catalyst and generate the aporphine skeleton in up to 99% yield.
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