An iterative approach to novel polyaminesvia nucleophilic ring-opening of aziridinium ions with β-amino alcohols

Literature Information

Publication Date 2004-04-01
DOI 10.1039/B401447B
Impact Factor 6.222
Authors

Christopher McKay, Robert J. Wilson, Christopher M. Rayner


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Abstract

An iterative procedure for the synthesis of a novel class of synthetic polyamines has been developed, utilising the regioselective ring-opening of aziridinium ion intermediates; facile N-allyl deprotection of intermediate polyamines allows the rapid construction of high molecular weight, stereochemically defined compounds in a convergent manner.

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