Absolute asymmetric synthesis by nucleophilic carbonyl addition using chiral crystals of achiral amides
Literature Information
Masami Sakamoto, Shuichiro Kobaru, Takashi Mino, Tsutomu Fujita
Reaction of the chiral crystals of the achiral amides with n-butyllithium in toluene at −80 °C gave optically active alcohols in 17–84% ee.
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Chemical Communications

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