A substituted triaza crown ether as a binding site in DNA conjugates

Literature Information

Publication Date 2003-03-18
DOI 10.1039/B301100C
Impact Factor 6.222
Authors

Stefan Vogel, Katja Rohr, Otto Dahl, Jesper Wengel


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Abstract

Synthesis of an asymmetrically substituted triaza crown ether, its incorporation into the 3′-end and 5′-end of nine-mer oligonucleotides, and the influence of various alkanediamine ligands on duplex thermostabilities are reported.

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Chemical Communications

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ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

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