The phenolortho-oxygenation by mononuclear copper(i) complexes requires a dinuclear μ-η2∶η2-peroxodicopper(ii) complex rather than mononuclear CuO2 species
Literature Information
Giuseppe Battaini, Marco De Carolis, Enrico Monzani, Felix Tuczek, Luigi Casella
The mononuclear complex [Cu(L)]+ performs the ortho-oxygenation of an exogeneous phenol through the formation of a dinuclear μ-η2∶η2-peroxodicopper(II) intermediate, which is so far the only type of copper–dioxygen complex that mediates the tyrosinase monophenolase reaction.
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![N-[4-(Cyanoethynyl)phenyl]-16-oxo-4,7,10,13-tetraoxa-17-azahenicos-1-yn-21-amide structure N-[4-(Cyanoethynyl)phenyl]-16-oxo-4,7,10,13-tetraoxa-17-azahenicos-1-yn-21-amide structure](https://static.chemtradehub.com/structs/218/2183440-36-8-68cb.webp)

amine structure [(2-chlorophenyl)methyl](ethyl)amine structure](https://static.chemtradehub.com/structs/629/62924-61-2-0728.webp)

